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MONKEYPOX-A REVIEW
  • Ashmita Banik,
  • Mika Umpo,
  • Sukanta Sinha
Ashmita Banik
Government of Arunachal Pradesh

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Mika Umpo
Government of Arunachal Pradesh
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Sukanta Sinha
Government of Arunachal Pradesh
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Abstract

Monkeypox is a viral zoonosis caused by monkeypox virus, an orthopoxvirus, structurally related to smallpox virus. Characterised by skin lesions such as rashes, concentrated on face, palms & soles. Two distinct clades are West African clade and Congo Basin clade, also called central African clade. Enveloped brick shaped virus, replicated in cytoplasm. Both humoral and cell mediated immunity are seen.Diagnosed by polymerase chain reaction (PCR) and various serological tests.Now a days supportive treatment is given along with antiviral drugs. Smallpox vaccines have role in protection, recently new Mpox vaccines are approved by FDA.Researches are needed to understand the effectiveness of treatment & prevention. This review consists of an updated version of monkeypox in human life in context of ongoing outbreaks around the world.