Advances in the study of the role of extraoral bitter taste receptors
AbstractTaste is one of the basic senses of living organisms and can recognize
sour, bitter, salty, sweet and umami tastes. Bitter taste receptor is a
class of G protein-coupled receptors capable of sensing bitterness.
Initially, bitter taste receptor was thought to be only found in the
taste buds of the tongue, palate and throat. Recent research has shown
that in addition to the oral cavity, the bitter taste receptor is also
present in the intestinal tract, respiratory tract, urinary tract,
vascular smooth muscle, nervous system, thyroid gland and other tissues
and organs to regulate body homeostasis and resist disorders . In this
review, we focus on the effects of the bitter taste receptor outside the
oral cavity to lay the groundwork for future research.