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Marburg Virus Disease Outbreaks in Equatorial Guinea and Tanzania: challenges and recommendations
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  • Mohammad Ali,
  • Muhammad Talha,
  • Muhammad Abdullah,
  • Ayesha Humayun
Mohammad Ali
Shaikh Khalifa Bin Zayed Al Nahyan Medical and Dental College

Corresponding Author:[email protected]

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Muhammad Talha
Shaikh Khalifa Bin Zayed Al Nahyan Medical and Dental College
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Muhammad Abdullah
Shaikh Khalifa Bin Zayed Al Nahyan Medical and Dental College
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Ayesha Humayun
Shaikh Khalifa Bin Zayed Al Nahyan Medical and Dental College
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Abstract

The current outbreak of Marburg Virus in Equatorial Guinea and Tanzania is a growing concern in Sub-Saharan African Region. With a mortality rate of upto 88%, lack of treatment and its transmissibility, it has a very high epidemic and pandemic potential. Unrestricted traveling can result in a global pandemic with ease. The virus is transmitted mainly via blood, skin puncture and fomites with secretions of an infected person or Rousette bat colonies. The symptoms are divided into three phases similar to the ebola virus. The average incubation period is about 5-9 days. Many experimental drugs are being developed revealing positive results like Favipravir (antiviral) and MR191-N (monoclonal antibody). Pre-exposure vaccines are currently in Phase 1 clinical trials. Post-exposure vaccines have also shown positive outcomes. Stakeholders within countries should take action with strong commitment by following instructions and warnings issued by WHO.