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Biomimetic Highly Ordered Apatite Coatings for Dental Implants
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  • Sherif Elsharkawy ,
  • Sara Gamea,
  • Natalia Karpukhina,
  • Maisoon Al-Jawad
Sherif Elsharkawy
King’s College Hospital Charity

Corresponding Author:[email protected]

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Sara Gamea
King's College London
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Natalia Karpukhina
Queen Mary University of London Barts and The London School of Medicine and Dentistry
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Maisoon Al-Jawad
University of Leeds School of Dentistry
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Bioactive coatings on metallic ‘titanium’ or ceramic ‘sapphire’ implants are known for their potential to promote bone biocompatibility, osseointegration, and long-term survival. In this study, we have investigated the effect of the surface topography of titanium and sapphire at different temperatures on the chemistry, morphology, organization, and coverage of the synthesized apatite coatings. We use a wet chemical method with a fluoride rich calcium-phosphate solution, to induce bioactive coatings onto etched titanium, non-etched titanium, polished and unpolished sapphire at 37, 70, and 90˚C. Fluoridated hydroxyapatite formation is detected across all temperatures using FTIR, synchrotron XRD, and MAS-NMR. Surface topography and temperature changes play a crucial role in the organization and coverage of the apatite crystals. Well-defined hexagonal nanocrystals are observed across each of the conditions, in the range between 35-81 nm. At lower temperatures, self-assembled organized nanocrystals appear to grow out from spherical structures, creating highly-ordered apatite architectures. However, at 90˚C, the nanocrystals seem to lack the hierarchical organization and appear to be arranged randomly. This work demonstrates a promising avenue for modifying implant surfaces with highly-ordered apatite-based coatings at physiological conditions.
26 Apr 2023Submitted to Engineering Reports
27 Apr 2023Review(s) Completed, Editorial Evaluation Pending
27 Apr 2023Submission Checks Completed
27 Apr 2023Assigned to Editor
28 Apr 2023Reviewer(s) Assigned
08 May 2023Editorial Decision: Revise Minor
02 Jun 20231st Revision Received
06 Jun 2023Submission Checks Completed
06 Jun 2023Assigned to Editor
06 Jun 2023Review(s) Completed, Editorial Evaluation Pending
16 Jun 2023Reviewer(s) Assigned
16 Jul 2023Editorial Decision: Revise Minor