Bacterial and viral coinfection among patients with COVID-19: a case
Background: Various studies suggest that coinfection with two or more
respiratory pathogens is common. Coinfection with two viruses affects
the host and exerts synergic effect as well and can influence the
disease pathogenesis, immune system responses and treatment and outcome.
Influenza and COVID-19 respiratory viruses have very similar symptoms
and for this reason, bring about problems including delayed treatment
and right diagnosis. This report describes three cases of coinfection
with COVID-19 and influenza. Case Presentation: First case is a 46 years
old Iranian housewife with the history of chronic coughs from two months
ago who presented with exacerbation of coughs together with dyspnea. The
second case is a 62 years old Iranian housewife with history of diabetes
mellitus type 2 (DM-2) who presented with productive coughs, dyspnea and
weakness. The third case is an Iranian pregnant housewife who presented
with myalgia, fever and chills and dry coughs from a week ago. All three
cases were tested positive for influenza and COVID-19 PCR tests.
Conclusion: coinfection with two viruses can result in synergism of
pathogens. Moreover, coinfection with a bacterial pathogen can make
further problems. In these cases, coinfection with two viruses and
mycobacterial infection in one of the cases along with comorbidities and
pregnancy implied that these conditions entail immediate diagnosis as
well as appropriate treatment choices.