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C-Glycoside Synthesis Enabled by Nickle Catalysis
  • Dawen Niu,
  • Weidong Shang,
  • Rong Shi
Dawen Niu
Sichuan University

Corresponding Author:[email protected]

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Weidong Shang
Sichuan University
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Rong Shi
Sichuan University
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C-Glycosides are critical, naturally occurring products and medicinal candidates, and extensive efforts have been made to explore efficient approaches for creating C-glycosidic bonds. Transition-metal-catalysis, particularly nickel-catalyzed C-glycosylation reactions constitute a promising strategy. However, achieving a stereoselective synthesis of α- and β-C-glycosides has been a long-standing challenge. To address this problem, a variety of nickel-mediated strategies have been developed. This review highlights recent developments in the nickel-catalyzed diastereoselective C-glycosylation reactions and briefly summarizes the mechanistic understandings of these methods.
20 Mar 2023Reviewer(s) Assigned
04 Apr 2023Review(s) Completed, Editorial Evaluation Pending
07 Apr 2023Editorial Decision: Revise Minor
10 Apr 20231st Revision Received
10 Apr 2023Submission Checks Completed
10 Apr 2023Assigned to Editor
10 Apr 2023Review(s) Completed, Editorial Evaluation Pending
10 Apr 2023Editorial Decision: Accept