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The Clinical Characteristics of Heart Rate Variability after Stroke: A Systematic Review
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  • Xue Bai,
  • Na Wang,
  • Yueqiao Si,
  • Yunchang Liu,
  • Ping Yin,
  • Chun-Mei Xu
Xue Bai
Army Medical University Daping Hospital
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Na Wang
Army Medical University Daping Hospital
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Yueqiao Si
Army Medical University Daping Hospital
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Yunchang Liu
Army Medical University Daping Hospital
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Ping Yin
Army Medical University Daping Hospital
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Chun-Mei Xu
Army Medical University Daping Hospital

Corresponding Author:[email protected]

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Abstract

Autonomic nervous system dysfunction has been reported in up to 76% of stroke patients 7 days after an acute stroke. Heart rate variability (HRV) is one of the important indicators reflecting the balance of sympathetic and parasympathetic nerves. Therefore, we performed a systematic literature review of existing literature on the association between heart rate variability and the different types of stroke. We included studies published in the last 32 years (1990–2022). The electronic databases MEDLINE and Pubmed were searched. We selected the research which met the inclusion or exclusion criteria. A narrative synthesis was performed. This review aimed to summarize evidence regarding the potential mechanism of heart rate variability among patients after stroke. In addition, the association of clinical characteristics of heart rate variability and stroke has been depicted. The review further discussed the relationship between post-stroke infection and heart rate variability, which could assist in curbing clinical infection in patients with stroke. HRV as a non-invasive clinical monitoring tool can quantitatively assess the changes in autonomic nervous system activity, and further predict the outcome of stroke. HRV could play an important role in guiding clinical practice for autonomic nervous system disorder after stroke.