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Otolith and balance function evolution related to cochlear implantation in hearing loss with inner ear malformations
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  • Mengya Shen,
  • Shujin Xue,
  • Xingmei Wei,
  • Biao Chen,
  • Ying Kong,
  • Yongxin Li
Mengya Shen
Beijing Tongren Hospital
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Shujin Xue
Beijing Tongren Hospital
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Xingmei Wei
Beijing Tongren Hospital
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Biao Chen
Beijing Tongren Hospital
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Ying Kong
Beijing Tongren Hospital
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Yongxin Li
Beijing Tongren Hospital

Corresponding Author:[email protected]

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Objectives: In recent years, with the incidence of bilateral cochlear implantation (CI) increasing, understanding the impact of CI on otolith function is of greater necessity. This study aims to investigate the development of gross motor and otolith function in patients with inner ear malformations (IEMs) by vestibular evoked myogenic potentials (VEMP). Materials and Methods: A total of 78 patients with sensorineural hearing loss (SNHL) (age 5.7±4.1 years) were divided into two groups based on the presence (IEM group, n=39) or absence (control group, n=39) of IEMs. VEMP was conducted before and 1–3 months after CI, and gross motor development assessed. Results: The mean ages of head control and independent walking were delayed in the IEM group compared with control group ( p=0.02). The preoperative cVEMP and oVEMP response rates were higher in the control groups (60% and 86.95%) than in the IEM group (57.69% and 74.35%) ( p<0.05). Additionally, abnormal cVEMP was associated with delayed acquisition of independent walking ( p=0.017). Saccular and utricular functions after CI were lost by 40% and 31.75%, respectively, in group of patients present preoperatively VEMPs waveform (n=25). Conclusions: Balance development is more reduced in patients with SNHL and IEMs than in patients without IEMs. The otolith-vestibular nerve conduction pathway can be affected by CI and lead to otolith function impairment. As such, evaluating the otolith and balance functions before CI is necessary and should be considered in clinical practice.
20 Feb 2023Submitted to Clinical Otolaryngology
23 Feb 2023Submission Checks Completed
23 Feb 2023Assigned to Editor
01 Mar 2023Reviewer(s) Assigned
25 Apr 2023Review(s) Completed, Editorial Evaluation Pending
21 May 2023Editorial Decision: Revise Major
10 Aug 20231st Revision Received
12 Aug 2023Submission Checks Completed
12 Aug 2023Assigned to Editor
29 Aug 2023Reviewer(s) Assigned
21 Oct 2023Review(s) Completed, Editorial Evaluation Pending