Characteristics and outcomes of pregnant patients and their infants in a
linked maternal-infant administrative claims database
Abstract
Purpose: Describe patient characteristics, pregnancy outcomes,
and infant outcomes among pregnant patients and their linked infants in
the novel Maternal Outcomes Masterset (MOM). Methods: We used
closed claims within the MOM data to identify publicly and
privately-insured patients at first record of pregnancy
1/1/2018-12/1/2021 with ≥180 days baseline enrollment. We described
characteristics during baseline and follow-up (until an observed
pregnancy endpoint, disenrollment, or 42-week maximum). We described
maternal and infant characteristics overall and by infant linkage.
Results: Among 1,438,861 pregnant patients meeting the study
criteria, the most common pregnancy endpoint recorded was live birth
(42%) followed by spontaneous abortion (14%). Among 602,721 patients
with a live birth, 99% had a week-specific gestational age recorded and
35% had at least one linked infant. Patients with infant linkage and
sufficient follow-up (N=155,621) had similar baseline comorbidities,
pregnancy complications, and gestational age at delivery versus those
without any linkage. However, more patients with linkage had commercial
coverage (70% vs 31%), and were therefore older (50% vs 31% aged ≥30
years) and more likely to have unknown race (57% vs 34%).
Conclusions: In this large sample of pregnant patients,
maternal and infant characteristics generally align with national
statistics, providing confidence in the use of this novel data source
for pregnancy research. Further, confirmation that the subset of
patients with infant linkage is similar to the overall pregnancy cohort
provides assurance that this subset can be considered representative.