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Conduction System Pacing: How far are we from the “electrical” bypass?
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  • Evangelos Sdogkos,
  • Konstantinos Iliodromitis,
  • Andrew Xanthopoulos,
  • Filippos Triposkiadis,
  • John Skoularigis,
  • Harilaos Bogossian,
  • Ioannis Vogiatzis
Evangelos Sdogkos
General Hospital of Veroia

Corresponding Author:[email protected]

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Konstantinos Iliodromitis
Evangelisches Krankenhaus Hagen Haspe
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Andrew Xanthopoulos
University Ηospital of Larissa
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Filippos Triposkiadis
University Ηospital of Larissa
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John Skoularigis
University Ηospital of Larissa
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Harilaos Bogossian
Evangelisches Krankenhaus Hagen Haspe
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Ioannis Vogiatzis
General Hospital of Veroia
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Abstract

Conduction system pacing is an alternative practice to conventional right ventricular apical pacing. It is a method that maintains physiologic ventricular activation, based on a correct pathophysiological basis, in which the pacing lead bypasses the lesion of the electrical fibers, and the electrical impulse transmits through the intact adjacent conduction system. For this reason, it might reasonably characterized by the term “electrical bypass” compared to the coronary artery bypass in revascularization therapy. In this review reference is made to the sequence of events that conventional right ventricular pacing may cause adverse outcomes. Furthermore, there is a reference to alternative strategies and pacing sites. Interest focuses on the modalities for which there is data from the literature, namely for the Right Ventricular (RV) septal pacing, the His Bunde pacing (HBP), and the Left Bundle Branch pacing (LBBP). A more extensive reference is about the HBP, for which there are the most updating data. We analyze the considerations that limit HBP wide application in three axes, and we also present the data for the implantation and follow-up of these patients. Then, the indications with their most important studies to date are described in detail, not only in their undoubtedly positive findings but also in their weak aspects, because of which, this pacing mode has not yet received a strong recommendation for implementation. Finally, there is a report on LBBP, focusing mainly on its points of differentiation from HBP.