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Use of deprescribing search filters in systematic review search strategies: a case study
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  • Thomas Morel,
  • Clara Heinrich,
  • Lorène Zerah,
  • Eoin Hurley,
  • Antoine Christiaens,
  • Jean-Pascal Fournier
Thomas Morel
Nantes University
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Clara Heinrich
University College Cork
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Lorène Zerah
Assistance Publique - Hopitaux de Paris
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Eoin Hurley
University College Cork
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Antoine Christiaens
Sorbonne Universite
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Jean-Pascal Fournier
Nantes University

Corresponding Author:jean-pascal.fournier@univ-nantes.fr

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Deprescribing search filters aiming at maximizing sensitivity for MEDLINE and for Embase were recently developed. Simultaneously, The US Deprescribing Network (USden) developed a deprescribing search strategy that included a deprescribing search filter for MEDLINE. The aim of this case study was to implement these deprescribing search filters in original search strategies from deprescribing related systematic reviews (SRs) and to calculate their performances. Two deprescribing SRs were included. Authors were asked to repeat the selection process described in SRs original methods. Performances of search strategies implemented with deprescribing search filters (ISS) were calculated and compared to original search strategies (OSS). In MEDLINE, sensitivity for SR 1 was 50% for OSS (Precision: 2.8%), 58% for ISS with maximised sensitivity filter (Precision: 1.7%) and 42% for ISS with USden filter (Precision: 5.1%). Sensitivity for SR 2 was 25% for all search strategies (Precision: 0.1%, 0.2% and 1,2% respectively). In Embase, sensitivity for SR 1 was 33% (Precision: 4,1%) for OSS and 58% for ISS (Precision 2.1%). No articles were included through Embase search strategies for SR 2. Using maximized sensitivity deprescribing filters may increase the exhaustivity of deprescribing SRs. Precision offered by the USDeN deprescribing filter is a convenient alternative for non-systematic reviews.
01 Feb 2023Submitted to Basic & Clinical Pharmacology & Toxicology
02 Feb 2023Assigned to Editor
02 Feb 2023Submission Checks Completed
02 Feb 2023Review(s) Completed, Editorial Evaluation Pending
02 Feb 2023Reviewer(s) Assigned
22 Mar 2023Editorial Decision: Revise Minor