Ferroptosis in female reproductive diseases: from potential pathogenesis
Ferroptosis, a cohering network integrating iron, amino acids, lipids,
and redox chemicals together，is a unique regulated cell death (RCD).
Iron overload, excessive reactive oxygen species (ROS), and lipid
peroxidation all contribute to the onset of ferroptosis. In recent
years, a growing body of evidence suggests that ferroptosis is
associated with some female reproductive diseases. The purpose of our
review is to give a brief description of ferroptosis activation
mechanism and relationship to female reproductive diseases including
infertility, pregnancy associated diseases and ovarian cancer.