Rare occurrence of Combined hepatocellular cholangiocellular carcinoma
in duck in India
AbstractCombined hepatocellular cholangiocellular carcinomas are the rarest form
of primary hepatic tumors in avian species. Many reports of cHCC-CCA
have been reported in animals with minimum reports in avian family. The
present article deals with the occurrence of cHCC-CCA in duck reported
to Veterinary pathology department, LUVAS. Grossly the duck was
emaciated with presence of blood in the abdominal cavity, pale enlarged
liver yellow to green raised firm nodules of varying sizes.
Histopathological examination confirmed mixed hepatic tumor as both
hepatocellular and cholangiocellular carcinoma lesions were evident.
Increased proliferation of the bile duct along with fatty change in
hepatocytes with altered cytoplasm-nuclei ration, anisokaryosis,
anisocytosis, binucleation and presence of mitotic figures. Special
staining revealed presence of thick fibrous capsule separating the tumor
masses. To our knowledge this is the first case of occurrence of
combined hepatocellular cholangiocellular carcinoma in duck in India.