Persulfate promoted carbamoylation of N-arylacrylamides with
4-carbamoyl-Hantzsch esters under metal-free conditions
4-Carbamoyl-Hantzsch esters were used as carbamoyl radical precursors
for oxidative carbamoylation of N-arylacrylamides in the presence of
inexpensive persulfates. This protocol can be applied for a broad range
of substrates with various functional groups, whereas a variety of
3,3-disubstituted oxindoles were obtained in good yields via an
intermolecular addition/cyclization process.