loading page

Outpatient respiratory outcomes in children with BPD on supplemental oxygen
  • +2
  • Sharon McGrath-Morrow,
  • Julianne McGlynn,
  • Brianna Aoyama,
  • Amanda Martin,
  • Joseph Collaco
Sharon McGrath-Morrow
The Children's Hospital of Philadelphia

Corresponding Author:[email protected]

Author Profile
Julianne McGlynn
The Children's Hospital of Philadelphia
Author Profile
Brianna Aoyama
Johns Hopkins University School of Medicine
Author Profile
Amanda Martin
The Children's Hospital of Philadelphia
Author Profile
Joseph Collaco
Johns Hopkins University School of Medicine
Author Profile


Introduction: Preterm children with bronchopulmonary dysplasia (BPD) frequently require supplemental oxygen in the outpatient setting. In this study, we sought to determine patient characteristics and demographics associated with need for supplemental oxygen at initial hospital discharge, timing to supplemental oxygen liberation, and associations between level of supplemental oxygen and likelihood of respiratory symptoms and acute care usage in the outpatient setting. Methods: A retrospective analysis of subjects with BPD on supplemental oxygen (O 2) was performed. Subjects were recruited from outpatient clinics at Johns Hopkins University and the Children’s Hospital of Philadelphia between 2008 and 2021. Data were obtained by chart review and caregiver questionnaires. Results: Children with BPD receiving > 1 liter of O 2 were more likely to have severe BPD, pulmonary hypertension and be older at initial hospital discharge. Children discharged on higher levels of supplemental O 2 were slower to wean to room air compared to lower O 2 groups (p<0.001). Additionally, weaning off supplemental O 2 in the outpatient setting was delayed in children with gastrostomy tubes and those prescribed inhaled corticosteroids, on public insurance or with lower estimated household incomes. Level of supplemental O 2 at discharge did not influence outpatient acute care usage or respiratory symptoms. Conclusion: BPD severity and level of supplemental oxygen use at discharge did not correlate with subsequent acute care usage or respiratory symptoms in children with BPD. Weaning of O 2 however was significantly associated with socioeconomic status and respiratory medication use, contributing to the variability in O 2 weaning in the outpatient setting.
19 Dec 2022Submitted to Pediatric Pulmonology
19 Dec 2022Submission Checks Completed
19 Dec 2022Assigned to Editor
19 Dec 2022Review(s) Completed, Editorial Evaluation Pending
21 Dec 2022Reviewer(s) Assigned
05 Jan 2023Editorial Decision: Revise Minor
31 Jan 20231st Revision Received
02 Feb 2023Submission Checks Completed
02 Feb 2023Assigned to Editor
02 Feb 2023Review(s) Completed, Editorial Evaluation Pending
02 Feb 2023Reviewer(s) Assigned
13 Feb 2023Editorial Decision: Accept