Streptococcus pneumoniae (S. pneumoniae) is the most important
pathogenic bacteria occurred in wide range of habitat, which cause of
several diseases, including pneumonia, meningitis, otitis media,
bacteremia and other common infections. Every year, approximately 1.6
million people are seriously affected and ultimately die as a result of
pneumococcal infections worldwide, affecting people’s lives and health.
Relevant studies in recent years have demonstrated the important role of
microRNAs (miRNAs) in a variety of diseases. Further research on the
mechanism of microRNA and the relationship between microRNA and diseases
has shown that microRNA may become a new biological marker for disease
diagnosis and may also provide a new approach to disease treatment. The
function of microRNA in pneumococcal infections has also been gradually
reported, including pneumococcal nasopharyngeal colonization, pneumonia,
sepsis, bacteremia, heart invasion, meningitis, acute otitis media,
osteoarthritis and other diseases. This article will overview the
mechanism and research progress of microRNA in infections caused by S.