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A Challenging Case of Beta-Lactam Induced Encephalopathy. A Case Report
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  • Shaikha Asheer,
  • Salihah Al Mani,
  • Ali Alshehri,
  • Mohammad Alasmri
Shaikha Asheer
King Hamad University Hospital

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Salihah Al Mani
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Ali Alshehri
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Mohammad Alasmri
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Beta-lactams are widely utilized as a first-line therapy with a broad-spectrum coverage, bactericidal properties and few side effects as they are commonly considered as safe drugs. Although these antibiotics are essential in the treatment of infections, their misuse and unnecessary prolonged duration may cause harm. Drug-induced neurotoxicity is a rare adverse reaction associated with beta-lactams. Encephalopathy is a type of neurotoxicity that is defined as a diffuse disease of the brain that alters brain function or structure. We report a case of a patient with normal renal function that developed beta-lactam induced encephalopathy with full resolution of her symptoms following discontinuation of the offending antibiotics. This case highlights the importance of early recognizing this rare adverse effect and its impact on clinical outcomes.