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Novel green synthesis of tin nanoparticles by medicinal plant: Chemical characterization and determination of cytotoxicity, anti-human lung cancer and antioxidant properties
  • Xiao Zou
Xiao Zou
Wuhan University Zhongnan Hospital

Corresponding Author:[email protected]

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In the present study, tin nanoparticles were green-synthesized using the aqueous extract of Foeniculum vulgare leaf aqueous extract. The synthesized SnNPs were characterized by analytical techniques including EDX, FE-SEM, XRD, UV-Vis., and FT-IR. The anti-human gastric cancer activity of SnNPs was evaluated using MTT assay. The nanoparticles were formed in a spherical shape in the range size of 26.45 to 38.53 nm. In the antioxidant test, the IC50 of F. vulgare, SnNPs@FV, and BHT against DPPH free radicals were 384, 119, and 71 µg/mL, respectively. In the cellular and molecular part of the recent study, the treated cells with SnNPs@FV were assessed by MTT assay for 48h about the cytotoxicity and anti-human lung cancer properties on normal (HUVEC) and lung cancer cell lines i.e., NCI-H2126, NCI-H1299, and NCI-H1437. The IC50 of SnNPs@FV were 108, 168, and 122 µg/mL against NCI-H2126, NCI-H1299, and NCI-H1437 cell lines, respectively. The viability of malignant lung cell line reduced dose-dependently in the presence of SnNPs@FV.
29 Oct 2022Submitted to Micro & Nano Letters
31 Oct 2022Submission Checks Completed
31 Oct 2022Assigned to Editor
11 Nov 2022Reviewer(s) Assigned
11 Nov 2022Review(s) Completed, Editorial Evaluation Pending
12 Nov 2022Editorial Decision: Revise Minor
21 Dec 20221st Revision Received
25 Dec 2022Submission Checks Completed
25 Dec 2022Assigned to Editor
26 Dec 2022Reviewer(s) Assigned
30 Dec 2022Review(s) Completed, Editorial Evaluation Pending
30 Dec 2022Editorial Decision: Accept