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Ongoing clinical observation of significance #2.7 - Rapid Corticosteroid-induced reduction of blood glucose level in a patient with a hereditary iron transport disorder H63D syndrome
  • +5
  • Dr. Carolina Diamandis,
  • David Seideman,
  • Lucas Smith,
  • Sofia Makri,
  • Benjamin Steinberg,
  • Martin Gangnon,
  • Adrian Tudor,
  • Olga Ivanova
Dr. Carolina Diamandis

Corresponding Author:[email protected]

Author Profile
David Seideman
Lucas Smith
Sofia Makri
Benjamin Steinberg
Martin Gangnon
Adrian Tudor
Olga Ivanova


Update 2.7
We report the case of a patient who suffers from hypotransferrinemia due to a genetic defect, subsequently suffers organ damage due to non-transferrin bound iron (NTBI) and develops a paradoxical reaction of glucose metabolism as a result of treatment with corticosteroids. To our knowledge, this is the first description of such an effect in the medical literature. The mechanism and further course of this phenomenon are currently still in the dark. Due to its peculiarity, we therefore publish only the clinical key data for the time being. We reported earlier about the same patient’s change in his narcolepsy symptoms.