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An overview of experimental methodologies for bioactive glass-coated Ti implants assessment in orthopedic and dental applications
  • +4
  • XinYue Lu,
  • Yu Ru Li,
  • XinRu Zheng,
  • XiaoYu Geng,
  • XuanYi Wang,
  • Dan Yang,
  • Heng Bo Jiang
XinYue Lu
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China

Corresponding Author:xinyuelu111@outlook.com

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Yu Ru Li
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
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XinRu Zheng
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
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XiaoYu Geng
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
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XuanYi Wang
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
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Dan Yang
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
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Heng Bo Jiang
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
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Abstract

Bioactive glass, as an ideal biomaterial, is not suitable for load-bearing parts because of its high brittleness and has been applied for surface modification to manufacture composite materials. Titanium alloy is bio-inert and prone to loosening, which leads to implant failure and infection after implantology. Applying bioactive glass to titanium and its alloys in the form of coating combines titanium metal's superior mechanical properties and bioglass's good biological properties. In this review, the authors searched and screened four databases, including Web of Science, PubMed, Embase, and Scopus, for articles published since 2013, finally, 49 articles were included to investigate the biological properties of bioactive glass coatings on titanium and its alloys. From the perspective of methodology, this review aims to summarize the methodologies performed for detecting the biological properties including biocompatibility and bioactivity of coatings were also concluded, covering the experimental process and principle of the included studies, therefore, providing learning materials for new researchers in material science and biotechnology.