Leadless pacing systems have revolutionized the field of
electrophysiology given its low complication rates and almost
non-existent rate of infections compared to traditional pacemakers.
These devices boast resistance to infections given its unique features;
however, as described in this report, device related infection from
these leadless devices is still possible. In patients with leadless
pacing system that are persistently bacteremic in the future, evaluation
of the device with transesophageal echocardiogram or intracardiac
echocardiography should be performed and if vegetation is noted on the
device, device extraction should highly be considered, along with
empiric intravenous antibiotics. Lastly, new leadless device should not
be re-implanted within 2 weeks of the removal of the infected device to
prevent seeding of the new device.