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A kinetic study of biotransformation from valencene to nootkatone in an oscillatory baffled reactor
  • Mohamed Chilmeran,
  • Matthew Hodges,
  • Xiong-Wei Ni
Mohamed Chilmeran
Heriot-Watt University School of Engineering and Physical Sciences

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Matthew Hodges
Oxford Biotrans Ltd
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Xiong-Wei Ni
Heriot-Watt University School of Engineering and Physical Sciences
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Abstract

In this paper we report our kinetic study of an oxidation reaction from valencene to nootkatone using enzyme in an oscillatory baffled reactor (OBR). A full kinetic model using the Langmuir-Hinshelwood formalism was established and applied to the experimental data, allowing reactor schemes and orders to be confirmed and reaction rate constants to be extracted. The analysis of reaction rate constants suggests that most of the reversible reaction steps can be treated as irreversible, simplifying reaction schemes. The effect of mixing intensity on the kinetics was also investigated.