loading page

Double Trouble: A Case of Fraternal Twins with Iron-Refractory Iron-Deficiency Anaemia
  • Jacques Malherbe,
  • Catherine Cole
Jacques Malherbe
Fiona Stanley Hospital

Corresponding Author:[email protected]

Author Profile
Catherine Cole
Saturn Pathology
Author Profile


Iron-refractory iron-deficiency anaemia (IRIDA) is a rare autosomal recessive disease that presents in childhood. We report the case of fraternal twins presenting with severe hypochromic microcytic anaemia and hypoferritinemia. Two missense mutations affecting the TRMPSS6 gene were identified, consistent with IRIDA. Subsequent parenteral iron therapy improved clinical and blood parameters.
12 Aug 2022Submitted to Clinical Case Reports
15 Aug 2022Assigned to Editor
15 Aug 2022Submission Checks Completed
16 Aug 2022Reviewer(s) Assigned
21 Sep 2022Review(s) Completed, Editorial Evaluation Pending
22 Sep 2022Editorial Decision: Accept
Oct 2022Published in Clinical Case Reports volume 10 issue 10. 10.1002/ccr3.6401