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Molecular Histology as a Novel Proxy for Ancient DNA and Protein Sequence Preservation
  • Landon A. Anderson
Landon A. Anderson
North Carolina State University at Raleigh
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Abstract

Researcher ability to accurately screen fossil and sub-fossil specimens for preservation of DNA and protein sequences remains limited. Thermal exposure and geologic age are usable proxies for sequence preservation on a broad scale but are of limited use for specimens of similar depositional environments and/or ages. Cell and tissue molecular histology is thus proposed as a proxy for determining sequence preservation potential of ancient specimens with improved accuracy. Molecular histology as a proxy is hypothesized to elucidate why fossil/sub-fossils of some depositional environments and or geologic ages preserve sequences while others do not and to facilitate selection of ancient specimens for use in molecular studies.
04 Jul 2022Submitted to Ecology and Evolution
05 Jul 2022Assigned to Editor
05 Jul 2022Submission Checks Completed
13 Jul 2022Reviewer(s) Assigned