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Preparation of high purity apigenin from Adinandra nitida leaves by antisolvent recrystallization method
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  • Li Wang,
  • Shen Li,
  • fengjian Yang,
  • xiuhua Zhao
Li Wang

Corresponding Author:904056916@qq.com

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fengjian Yang
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xiuhua Zhao
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High purity apigenin(AP) was prepared by antisolvent recrystallization method from old Adinandra nitida leaves. The procedure was as follows: Adinandra nitida leaves were extracted by boiling water, and the extracting solution was hydrolyzed with sulfuric acid to obtain crude apigenin(58.9%); the purity of crude apigenin was further improved by antisolvent recrystallization method. A satisfactory purity(98.47%) and yield(86.65%) was obtained under the optimum purifying condition. Scanning electronic microscopy(SEM),differential scanning calorimetry(DSC), Fourier transform infrared spectroscopy(FTIR) and HPLC-MS/MS were investigated.