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Electrographic Flow Mapping for Persistent Atrial Fibrillation: Theoretical Basis and Preliminary Observations
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  • David Haines,
  • Melissa H. Kong,
  • Peter Ruppersberg,
  • Philip Haeusser,
  • Boaz Avitall,
  • Tamas Szili-Torok,
  • Atul Verma
David Haines
Oakland University William Beaumont School of Medicine

Corresponding Author:david.haines2@beaumont.edu

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Melissa H. Kong
Jefferson County Public Library Wheat Ridge Library
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Peter Ruppersberg
Jefferson County Public Library Wheat Ridge Library
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Philip Haeusser
Jefferson County Public Library Wheat Ridge Library
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Boaz Avitall
University of Illinois Chicago College of Medicine
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Tamas Szili-Torok
Erasmus Universiteit Rotterdam Opleiding Bestuurskunde
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Atul Verma
Southlake Regional Health Centre
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Ablation strategies remain poorly defined for persistent atrial fibrillation (AF) patients with recurrence despite intact pulmonary vein isolation (PVI). As the ability to perform durable PVI improves, the need for advanced mapping to identify extra-PV sources of AF becomes increasingly evident. Multiple mapping technologies attempt to localize these self-sustained triggers and/or drivers responsible for initiating and/or maintaining AF; however, current approaches suffer from technical limitations. Electrographic flow (EGF) mapping is a novel mapping method based on well-established principles of optical flow and fluid dynamics. It enables the full spatiotemporal reconstruction of organized wavefront propagation within the otherwise chaotic and disorganized electrical conduction of AF. Given the novelty of EGF mapping and relative unfamiliarity of most clinical electrophysiologists with the mathematical principles powering the EGF algorithm, this paper provides an in-depth explanation of the technical/mathematical foundations of EGF mapping and demonstrates clinical applications of EGF mapping data and analyses.