Brain abscess complicating hemophagocytic lymphohistiocytosis and
Kawasaki disease in child: A case report
Abstract
We present a case of immunocompetent boy with brain abscess (BA)
complicating hemophagocytic lymphohistiocytosis (HLH) and Kawasaki
disease (KD), which is rarely reported. During the recovery period of
BA, he had another fever accompanied by enlarged lymph nodes, eye
conjunctival congestion, strawberry tongue, swelling on hands and feet,
and exanthema. Simultaneously, further investigations revealed
bicytopenia, liver dysfunction, hyperferritinemia, coagulopathy and
hemophagocytosis. The patient was treated with antibiotics, intravenous
immunoglobulin (IVIG) and steroid that led to rapid resolution. Our
report highlights the importance of early detection and treatment of
HLH, and possible resolution without using immunosuppressive therapy in
infectious patients.