Diagnostic challenges of pericardial mesothelioma: A case report and
review of literature
Abstract
Primary pericardial malignant mesothelioma (PPMM) is a rare malignancy
arising from the serous mesothelial lining of the pericardium. These
neoplasms are aggressive, pose diagnostic difficulties, and have a poor
prognosis. The median survival is less than six months. Presenting
symptoms are non-specific and include fatigue, dyspnea, and low-grade
fever. Given the nature of presenting symptoms, it is imperative that
appropriate imaging, tissue sampling, and histological analysis are
undertaken to establish a clinical diagnosis. In cases of localised
disease, surgical resection remains the primary treatment. In advanced
disease, chemotherapy or palliative procedures may be beneficial. We
describe two cases of PPMM and provide an update and guidance on the
contemporaneous management of this challenging condition.