loading page

Evaluating the predictive value of fetal Doppler indices and neonatal outcome in late-onset preeclampsia with severe features: A cross-sectional study in a resource-limited setting
  • +2
  • Eman Moawad,
  • Amr Samir Fouad Tammam,
  • Maha Mohamed Mosaad,
  • Hadeer Mashaal El Sayed,
  • Adel Mohammed Atef Mohammed Elaimy
Eman Moawad
Cairo University Kasr Alainy Faculty of Medicine

Corresponding Author:[email protected]

Author Profile
Amr Samir Fouad Tammam
Cairo University Kasr Alainy Faculty of Medicine
Author Profile
Maha Mohamed Mosaad
Cairo University Kasr Alainy Faculty of Medicine
Author Profile
Hadeer Mashaal El Sayed
Cairo University Kasr Alainy Faculty of Medicine
Author Profile
Adel Mohammed Atef Mohammed Elaimy
Cairo University Kasr Alainy Faculty of Medicine
Author Profile

Abstract

Background: Preeclampsia constitutes a major health problem with substantial maternal and perinatal morbidity and mortality. Purpose: The aim of this study was to detect the diagnostic efficacy of fetal Doppler in predicting adverse outcomes in severe late onset preeclampsia (LOP). Methods: A prospective study was conducted among childbearing women who presented with severe LOP and matched controls. Umbilical artery (UA) and middle cerebral artery (MCA) Doppler indices including pulsatility index (PI), resistance index (RI), systolic/diastolic ratio (S/D) and cerebroplacental ratio (CPR) were measured. Results: All UA indices were significantly higher in the case group compared to the controls (p  0.001). UA PI and RI were significantly correlated with all neonatal adverse outcomes except cord pH status (p  0.05). Abnormal CPR was the most sensitive index that positively correlated with intrauterine growth retardation (IUGR), low 5- minute Apgar score and neonatal intensive care unit admission (79 %, 72.8 % and 73.3 %, respectively). In the same context, Abnormal UA PI and RI represented the most specific tool for predicting IUGR, low 1- and 5- minutes Apgar score with PPV values were 52 %, 87 % and 57 %, respectively. Discussion: Doppler flow ultrasound has emerged as a non-invasive tool for fetomaternal surveillance in high risk pregnancies and prediction of adverse-pregnancy outcomes particularly in a limited-resource settings. Conclusion: In severe LOP, UA Doppler remains the preferential indicator for adverse birth outcomes with CPR is the best index that could be solely used for predicting such outcome.