Background: The safety and effectiveness of laparoscopic mini-gastric bypass (MGB) versus laparoscopic sleeve gastrectomy (LSG) remain unclear. In this study, we aimed to compare the postoperative outcomes of MGB and LSG procedures performed in bariatric surgery. Methods: A total of 363 patients who underwent MGB and LSG surgery between 2016 and 2018 at a single metabolic surgery center were analyzed retrospectively. Two surgical procedures were compared in terms of the perioperative, early and late postoperative outcomes. Results: There were 225 patients in the MGB group and 138 patients in the LSG group. No significant difference was found between the groups regarding the operating time, the conversion to open surgery and the early postoperative complications (p>0.05). The length of hospital stay was significantly shorter in the MGB group (p:0.001). The excess weight loss (EWL) was significantly higher in the MGB group (90.3 ± 13 vs. 79.2 ± 16). No significant difference was found between the two groups in terms of the remission rates of comorbidities. The symptoms of gastroesophageal reflux disease were observed in a significantly fewer number of the patients in the MGB group (6 patients 4.9% vs. 10 patients 18.5%). Conclusions: The MGB procedure is superior to the LSG in terms of the length of hospital stay, EWL, and the postoperative gastroesophageal reflux parameters.