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Preferences for multipurpose technology and non-oral methods of antiretroviral therapy among women living with HIV in western Kenya: a survey study
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  • Caitlin Bernard,
  • Beatrice Jakait,
  • William Fadel,
  • A. Mocello,
  • Maricianah Onono,
  • Elizabeth Bukusi,
  • Kara Wools-Kaloustian,
  • Craig Cohen,
  • Rena Patel
Caitlin Bernard
Indiana University School of Medicine

Corresponding Author:[email protected]

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Beatrice Jakait
Moi Teaching and Referral Hospital
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William Fadel
Indiana University School of Medicine
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A. Mocello
University of California San Francisco
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Maricianah Onono
Kenya Medical Research Institute
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Elizabeth Bukusi
Kenya Medical Research Institute
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Kara Wools-Kaloustian
Indiana University School of Medicine
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Craig Cohen
University of California San Francisco
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Rena Patel
University of Washington Department of Medicine
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Abstract

Objective: To understand the preferences of women living with HIV (WLHIV) for methods of multipurpose technology (MPT) for the co-administration of contraception and antiretroviral therapy (ART) and non-oral ART to guide their development and implementation. Design: A cross-sectional telephone survey as part of a study of pregnancy incidence among contraception and ART users Setting: Our study was performed in western Kenya Population: We included 1132 WLHIV of reproductive potential with prior experience using injectable and long-acting contraception Methods: We performed descriptive statistics and multinomial logistic regression Main Outcome Measures: Main outcomes were interest in MPT, important characteristics and preferred methods for MPT and non-oral ART, and predictors of interest in specific methods Results: Two-thirds (67%) reported interest in MPT, most commonly due to ease of using a single medication for both HIV treatment and pregnancy prevention (26%). Main reasons for lack of interest in MPT were need to stop/not use contraception while continuing ART (21%) and risk of side effects (16%). Preferred methods for MPT and non-oral ART were injectables (50%, 54%) and implants (32%, 31%). Prior use of a contraceptive implant or injectable predicted interest in similar methods for MPT and non-oral ART, and this did not vary by age. Conclusions: Many WLHIV in western Kenya are interested in MPT for contraception and ART. Prior experience with contraceptive implants and injectables predicts interest in similar methods of MPT and non-oral ART. Funding: NIH NIAID (K23AI120855) and the NIH NIAID, NICHD, NIDA, NCI, & NIMH for the EA-IeDEA Consortium (U01AI069911)