ABSTRACT Objectives: The leading purpose of this investigation is to measure the excellence of drug treatment by likeable in the assessment of data on drug prescribing, dispensing, administering and use of drugs by patient. Material & Methods: The study was planned to be a retrospective, assessing the prescribing design concerned about the utilization of anti-biotic in the management of various infections, throughout a period of two months January 2017 to February 2017 (approximately 60 days). The study was conducted at tertiary care hospital in which the prescriptions of 200 patients from the medical wards, were evaluated, in which 57 (28.5%) were females and 143 (71.5%) were males. Results: Mostly prescribed antibiotic were ceftriaxone 105 (34.09%), amoxicillin/clavulanic acid 18 (5.84%), moxifloxacin 35 (11.36%), metronidazole 55 (17.85%), azithromycin 7 (2.27%), sulbactam/cefoperazone 22 (7.14%), doxycycline 13 (4.22%), ciprofloxacin 40 (12.98%), cefotaxime 5 (1.62%), and clarithromycin 3 (0.97%). Total number of drugs prescribed were 1643 in which the average number of drugs encountered per prescription were 8.21, the percentage of encounters with antibiotics were 308 (18.74%), the percentage of encounter with injections were 897 (54.59%), the percentage of drugs prescribed by generic name were 205 (12.47%), and the percentage of drugs prescribed from EDL were 1367 (83.20%). Conclusion: On the bases of our study, the pattern used at Saidu Group of Teaching Hospital for the, prescription of antibiotics, injections, generic concept and drugs from EDL shows deviation from the standards guidelines of WHO.