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Title Acute efavirenz intoxication in a 16-year-old HIV negative girl: A case report and literature review
  • Minoo Moghimi,
  • Zahra Nekoukar,
  • Navid Khosravi
Minoo Moghimi
Mazandaran University of Medical Sciences
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Zahra Nekoukar
Mazandaran University of Medical Sciences Faculty of Pharmacy
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Navid Khosravi
Mazandaran University of Medical Sciences
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Abstract

Abstract We present an acute intoxication with 12 grams of efavirenz (EFV) in a 16-year-old healthy girl whose main problem was neurotoxicity which is dose-dependent. No other serious EFV-related side effects were seen. Previous serious side effects of EFV were observed in HIV-infected patients who underwent long-term combination drug therapy.