Lamin heart disease with ventricular noncompaction and complex atrial
septal arrhythmias: successful use of charge density mapping.
Abstract
Lamin A/C Mutations are important to recognized for therapeutic and
prognostic reasons. We present the clinical cases of two sisters with
Lamin A mutation presenting with complex atrial arrhythmias,
atrioventricular block and ventricular arrhythmias, associated with
ventricular noncompaction and abnormal pulmonary vein anatomy. The
successful treatment of complex irregular atrial arrhythmias by the use
of noncontact dipole density mapping and radiofrequency ablation (RFA)
is described in both sisters with long-term follow up results.