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Second Cancer Risk in Childhood Cancer Survivors Treated With Intensity-Modulated Radiation Therapy (IMRT): An Updated Analysis of More Than 10 Years of Follow-Up
  • +4
  • Kathryn Tringale,
  • Dana Casey,
  • Gregory Niyazov,
  • Jessica Lavery,
  • Chaya Moskowitz,
  • Danielle Novetsky Friedman,
  • Suzanne Wolden
Kathryn Tringale
Memorial Sloan Kettering Cancer Center
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Dana Casey
University of North Carolina System
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Gregory Niyazov
Memorial Sloan Kettering Cancer Center
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Jessica Lavery
Memorial Sloan Kettering Cancer Center
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Chaya Moskowitz
Memorial Sloan Kettering Cancer Center
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Danielle Novetsky Friedman
Memorial Sloan Kettering
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Suzanne Wolden
Memorial Sloan Kettering Cancer Center
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Abstract

Background It is unclear how intensity-modulated radiation therapy (IMRT) impacts long-term risk of second malignant neoplasms (SMNs) in childhood cancer patients. Procedure Patients aged 10 years, many solid SMNs after IMRT in childhood cancer survivors develop in the high dose region. These data serve as a foundation for comparison with other modalities of radiation treatment (e.g., proton therapy).

Peer review status:Published

22 Dec 2021Assigned to Editor
22 Dec 2021Submission Checks Completed
22 Dec 2021Submitted to Pediatric Blood & Cancer
24 Dec 2021Reviewer(s) Assigned
05 Jan 2022Review(s) Completed, Editorial Evaluation Pending
08 Jan 2022Editorial Decision: Revise Major
Nov 2021Published in International Journal of Radiation Oncology*Biology*Physics volume 111 issue 3 on pages e170-e171. 10.1016/j.ijrobp.2021.07.653