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Optimizing nanoencapsulation of Heracleum Lasiopetalum by response surface methodology
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  • Mahsa Yazdan-Bakhsh,
  • Mojtaba Nasr-Esfahani,
  • reza esmaeilzadeh kenari,
  • Mohamad Fazel-Najafabadi
Mahsa Yazdan-Bakhsh

Corresponding Author:[email protected]

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Mojtaba Nasr-Esfahani
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reza esmaeilzadeh kenari
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Mohamad Fazel-Najafabadi
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This study was carried out to optimize formulation for Heracleum Lasiopetalum (golpar) extract nanoencapsulation by response surface methodology (RSM). The primary emulsion was fabricated by (5-10 %) golpar extract (GE), (40-35 %) emulsifier span 80 (EM), and (50-60 %) sunflower oil (SO). The coating materials of nanoencapsulation were the composition of Lepidium sativum seed gum (LSG) and whey protein concentrate (WPC) at different ratios (1:0, 1:1, and 0:1). The yield of nanoencapsulation of golpar extract, particle size, and zeta potential was investigated as responses of RSM. The optimal formulation for nanoencapsulation of golpar extract were SO: 50.46%, GE 9.52%, and EM: 36.30% in LSG, SO: 57.07%, GE: 7.12%, and EM: 30.85% in LSG:WPC, and SO: 54.98%, GE: 9.05%, and EM: 39.87% in WPC coating. In conclusion, the nanoencapsulation of golpar extract prepared with the optimized formulation by RSM ensures the gradual release and sedimentation during storage with nanometric size and high yield of encapsulation. The nanocapsules of golpar extract can be used as a natural antioxidant in food systems.
13 Dec 2021Submitted to Journal of the American Oil Chemists' Society
13 Dec 2021Submission Checks Completed
13 Dec 2021Assigned to Editor
14 Dec 2021Reviewer(s) Assigned
12 Jan 2022Review(s) Completed, Editorial Evaluation Pending
28 Jan 2022Editorial Decision: Revise Major
22 Feb 20221st Revision Received
22 Feb 2022Assigned to Editor
22 Feb 2022Submission Checks Completed
24 Feb 2022Reviewer(s) Assigned
01 Mar 2022Review(s) Completed, Editorial Evaluation Pending
10 Mar 2022Editorial Decision: Revise Minor
10 Mar 20222nd Revision Received
10 Mar 2022Assigned to Editor
10 Mar 2022Submission Checks Completed
13 Mar 2022Review(s) Completed, Editorial Evaluation Pending
16 Mar 2022Editorial Decision: Accept
May 2022Published in Journal of the American Oil Chemists' Society volume 99 issue 5 on pages 421-431. 10.1002/aocs.12588