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Successful use of veno-venous extracorporeal membrane oxygenation for acute chest syndrome in a child with sickle cell disease and SARS-CoV-2
  • +2
  • Wonshill Koh,
  • Punam Malik,
  • Jason Whitehead,
  • David Morales,
  • Don Hayes
Wonshill Koh
Cincinnati Children's Hospital Medical Center
Author Profile
Punam Malik
Cincinnati Children's Hospital Medical Center
Author Profile
Jason Whitehead
Cincinnati Children's Hospital Medical Center
Author Profile
David Morales
Cincinnati Children's Hospital Medical Center
Author Profile
Don Hayes
Cincinnati Children's Hospital Medical Center
Author Profile

Abstract

Children with sickle cell disease (SCD) are at increased risk for severe illness due to severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). We describe the successful native lung recovery of a child with SCD referred for lung transplant (LTx) evaluation who was on prolonged veno-venous extracorporeal membrane oxygenation (VV-ECMO). He initially presented with acute chest syndrome complicated by SARS-CoV-2 infection that ultimately required dual-lumen, single bicaval VV-ECMO cannulation for respiratory support. Despite increased risk of hemolysis and thrombosis from SCD and SARS-CoV-2 infection, he was successfully supported on VV-ECMO for 71 days without complications leading to native lung recovery with meticulous management of his SCD therapy. This report provides new insight on our approach to VV-ECMO support in a child with SCD and SARS-CoV-2 infection. With a successful outcome, the patient has returned home but still on mechanical ventilation with LTx still an option if he is not eventually liberated from invasive respiratory support.
15 Nov 2021Submitted to Pediatric Pulmonology
16 Nov 2021Submission Checks Completed
16 Nov 2021Assigned to Editor
17 Nov 2021Reviewer(s) Assigned
07 Dec 2021Review(s) Completed, Editorial Evaluation Pending
07 Dec 2021Editorial Decision: Revise Minor
14 Dec 20211st Revision Received
14 Dec 2021Assigned to Editor
14 Dec 2021Submission Checks Completed
14 Dec 2021Reviewer(s) Assigned
30 Dec 2021Review(s) Completed, Editorial Evaluation Pending
01 Jan 2022Editorial Decision: Revise Minor
07 Jan 20222nd Revision Received
07 Jan 2022Submission Checks Completed
07 Jan 2022Assigned to Editor
07 Jan 2022Reviewer(s) Assigned
21 Jan 2022Review(s) Completed, Editorial Evaluation Pending
21 Jan 2022Editorial Decision: Accept
Apr 2022Published in Pediatric Pulmonology volume 57 issue 4 on pages 1096-1099. 10.1002/ppul.25843