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Variations in infection control practices suggest a need for guidelines in primary ciliary dyskinesia patient care
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  • Ayse Caliskan,
  • Amjad Horani,
  • Michele Manion,
  • Steven Brody
Ayse Caliskan
Washington University in Saint Louis
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Amjad Horani
Washington University in Saint Louis
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Michele Manion
PCD Foundation
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Steven Brody
Washington University in Saint Louis
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Abstract

Primary ciliary dyskinesis (PCD) is an autosomal recessive disorder associated with impaired mucociliary clearance caused by defects in ciliary structure and function. The major clinical feature of PCD is recurring or persistent respiratory tract infection. Respiratory tract colonization with drug-resistant organisms impact the frequency of infections and lung function decline. Protective gear has been employed by caregivers in an attempt to control respiratory tract bacterial spread between patients with cystic fibrosis but use in PCD is not known. We conducted a web-based survey to investigate infection control and prevention practices of PCD centers in North America. The response rate was 87.0%. Prior to the COVID-19 pandemic, glove, gown and mask use was variable, and only 3.7% of centers used masks during encounters with PCD outpatients. After COVID-19 mandates are lifted, 48.1% of centers plan to continue to use masks during outpatient care, while the practice regarding use of gloves and gowns was not influenced by the current pandemic. There is no uniform practice for infection control in PCD care indicating the need for practice guidelines. Mitigation of respiratory virus transmission learned during the COVID-19 pandemic may impact future infection control approaches used for patients with PCD and other lung diseases.
21 Oct 2021Submitted to Pediatric Pulmonology
21 Oct 2021Submission Checks Completed
21 Oct 2021Assigned to Editor
28 Oct 2021Reviewer(s) Assigned
19 Nov 2021Review(s) Completed, Editorial Evaluation Pending
24 Nov 2021Editorial Decision: Revise Minor
24 Nov 20211st Revision Received
25 Nov 2021Submission Checks Completed
25 Nov 2021Assigned to Editor
25 Nov 2021Reviewer(s) Assigned
21 Dec 2021Review(s) Completed, Editorial Evaluation Pending
18 Jan 2022Editorial Decision: Accept
Apr 2022Published in Pediatric Pulmonology volume 57 issue 4 on pages 1072-1075. 10.1002/ppul.25836