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Diagnostic accuracy of nasal endoscopy and contrast magnetic resonance imaging in COVID-19 associated mucormycosis (CAM)
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  • Nadeem Shaikh,
  • Neha Shakrawal,
  • Mahendra Chouhan,
  • Bharti Solanki
Nadeem Shaikh
Dr Sampurnanand Medical College
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Neha Shakrawal
Dr Sampurnanand Medical College
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Mahendra Chouhan
Dr Sampurnanand Medical College
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Bharti Solanki
Dr Sampurnanand Medical College
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Abstract

Key Points 1. COVID-19 associated mucormycosis (CAM) is a life-threatening fungal disease that has become an epidemic and notifiable disease after the second wave of COVID-19 in India 2. The target group for CAM includes severely immunocompromised individuals either by COVID-19, or corticosteroid therapy, or uncontrolled glycemic index. 3. With an intention to find out the sensitivity and specificity of diagnostic nasal endoscopy (DNE) and contrast-enhanced magnetic resonance imaging (CEMRI), one hundred two consecutive patients of target group with clinical features of CAM were enrolled in the study. 4. The sensitivity and specificity of DNE as compared to KOH mount were 73.4% and 94.7% respectively. The sensitivity and specificity of CEMRI as compared to KOH mount were 87.5% and 50% respectively. 5. CEMRI misses fewer cases than DNE. In cases of normal endoscopy in the target group, imaging and biopsy should be advised to reduce false-negative results. Nasal endoscopy, biopsy, and imaging can reliably detect the majority of cases of CAM.
30 Sep 2021Submitted to Clinical Otolaryngology
04 Oct 2021Submission Checks Completed
04 Oct 2021Assigned to Editor
19 Oct 2021Reviewer(s) Assigned
09 Nov 2021Review(s) Completed, Editorial Evaluation Pending
13 Nov 2021Editorial Decision: Revise Major
29 Jan 20221st Revision Received
03 Feb 2022Submission Checks Completed
03 Feb 2022Assigned to Editor
09 Feb 2022Reviewer(s) Assigned
17 May 2022Review(s) Completed, Editorial Evaluation Pending