ArVirInd - a database of arboviral antigenic proteins from the Indian
subcontinent
Abstract
Studies on antigenic proteins for arboviruses are important for
providing diagnostics and vaccine development. India and its
neighbouring countries have huge burden of arboviral diseases. Data
mining for country-specific sequences from existing databases is
cumbersome and time-consuming. This necessitated the development of a
database of antigenic proteins from arbo-viruses isolated from the
countries of the Indian subcontinent. Arboviral antigenic protein
sequences were obtained from the NCBI and other databases. In silico
antigenic characterization was performed (Epitope predictions) and data
incorporated in the database. The front end is designed and developed
using HTML, CSS and PHP. For the backend of the database, we have used
MySQL. A database, named ArVirInd, is created as a repository of
information on antigenic proteins. This enlists sequences by country and
year of outbreak or origin of the viral strain. For each entry antigenic
information is provided along with functional sites, etc. Researchers
can search this database by virus/protein name, country and year of
collection (or in combination). It is available publicly via Internet at
http://www.arvirind.co.in. ArVirInd will be useful in the study of
immuno-informatics, diagnostics and vaccinology for arboviruses.