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Multifocal periapical cement dysplasia in Ehlers-Danlos Typ VIII combined with leukoencephalopathy in de novo-mutation of c.890G>A, G297D [pEDS]
  • +3
  • Manfred Nilius,
  • MInou Nilius,
  • Charlotte Mueller,
  • Guenter Lauer,
  • Berit Koch,
  • Marcus Kohlhaas
Manfred Nilius
TU Dresden

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MInou Nilius
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Charlotte Mueller
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Guenter Lauer
TU Dresden
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Berit Koch
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Marcus Kohlhaas
Sankt-Johannes-Hospital Dortmund
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Periodontal Ehlers-Danlos syndrome type VIII (pEDS) is rare and caused by mutation in complement 1 subunit. Lack of attached gingiva, pretibial plaques, joint mobility, skin fragility, and easy bruising consolidate the diagnosis. We describe a case of de novo-mutation of pEDS with generalized periapical cemento dysplasia (PCD) and leukoencephalopathy.
02 Sep 2021Submitted to Clinical Case Reports
03 Sep 2021Submission Checks Completed
03 Sep 2021Assigned to Editor
12 Oct 2021Reviewer(s) Assigned
11 Feb 2022Review(s) Completed, Editorial Evaluation Pending
18 Feb 2022Editorial Decision: Revise Minor
13 May 20221st Revision Received
17 Sep 2022Submission Checks Completed
17 Sep 2022Assigned to Editor
17 Sep 2022Review(s) Completed, Editorial Evaluation Pending
26 Sep 2022Editorial Decision: Accept