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Echocardiographic parameters of left ventricular non-systolic function predict length of stay following coronary artery bypass graft -- a prospective observational study
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  • samhati Mondal,
  • Nauder Faraday,
  • Weidong Gao,
  • Sarabdeep Singh,
  • Sachidanand Hebbar,
  • Kimberly Hollander,
  • Thomas Metkus,
  • Lee Goeddel,
  • Maria Bauer,
  • Brian Bush,
  • Brian Cho,
  • Stephanie Cha,
  • Stephanie Ibekwe,
  • Domagoj Mladinov,
  • Noah Rolleri,
  • Laeben Lester,
  • Jochen Steppan,
  • Rosanne Sheinberg,
  • Nadia Hensley,
  • Anubhav Kapoor,
  • Jeffrey Dodd-o
samhati Mondal
University of Maryland School of Medicine

Corresponding Author:[email protected]

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Nauder Faraday
Johns Hopkins Medicine
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Weidong Gao
Johns Hopkins Medicine
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Sarabdeep Singh
Johns Hopkins Medicine
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Sachidanand Hebbar
Johns Hopkins Medicine
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Kimberly Hollander
University of Maryland School of Medicine
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Thomas Metkus
Johns Hopkins Medicine
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Lee Goeddel
Johns Hopkins Medicine
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Maria Bauer
Johns Hopkins Medicine
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Brian Bush
Johns Hopkins Medicine
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Brian Cho
Johns Hopkins Medicine
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Stephanie Cha
Johns Hopkins Medicine
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Stephanie Ibekwe
Ben Taub General Hospital
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Domagoj Mladinov
University of Alabama at Birmingham HCOP
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Noah Rolleri
University of Pittsburgh Medical Center
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Laeben Lester
Johns Hopkins Medicine
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Jochen Steppan
Johns Hopkins Medicine
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Rosanne Sheinberg
Johns Hopkins Medicine
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Nadia Hensley
Johns Hopkins Medicine
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Anubhav Kapoor
Mercy General Hospital
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Jeffrey Dodd-o
Johns Hopkins Medicine
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Abstract

Background: Abnormal left ventricular (LV) echocardiographic parameters during non-systolic phase, with or without a diagnosis of heart failure, is a common finding that can be easily diagnosed by intra-operative transesophageal echocardiography (TEE). However, its association with duration of hospital stay after coronary artery bypass (CAB) is unknown. Objective: To determine if Abnormal left ventricular (LV) echocardiographic parameters during non-systolic phase is associated with length of hospital stay after coronary artery bypass surgery (CAB). Method: Prospective observational study at a single tertiary academic medical center Result: Median time to hospital discharge was significantly longer for subjects with abnormal left ventricular (LV) echocardiographic parameters during non-systolic phase (9.1/IQR 6.6-13.5 days) than those with normal LV non-systolic function (6.5/IAR 5.3-9.7days) (P< 0.001). The probability of hospital discharge was 34% lower (HR 0.66/95% CI 0.47-0.93) for subjects with abnormal LV function even during non-systole despite a normal LV systolic function, independent of potential confounders, including a baseline diagnosis of heart failure Conclusions and Relevance: In patients with normal systolic function undergoing CAB, non-systolic LV dysfunction is associated with prolonged duration of postoperative hospital stay. This association cannot be explained by baseline comorbidities or common post-operative complications.