Abstract

Fabrication of biomaterials for Tissue Engineering application by bioprinting has gained enormous attention in the research field, owing to their rapid and reproducibility factor. Progress in organic based mesoporous particles is of great interest in order to accomplish in tissue engineering treatments. Recently, researchers are focusing on different 3D bioinks for attaining 3D matrices to accommodate the drugs and cells for biological efficacies. Bioprinting is a promising field of biomaterials and regenerative medicine for the next generation therapeutics. Different polymeric substances are being evaluated for their printablity based on their rheological and biological properties. Structural fidelity is stabilized by crosslinking methods and their adaptability to microenvironment is assessed using Invitro assays. External Factors such as concentration, temperature, medium and crosslinking agents are the critical determinants for the bionks to achieve the required functionality. Moreover, the choice base chemicals used for the formulation plays a vital role in the cell viability and proliferation that lead to specific tissue growth. The mechanical strength, elastic moduli to bear strength is anchored by the porous nature of the printed scaffolds. Therefore, the influence of porosity in the mechanical and biological strength adds an appropriate value to the printed biomaterial. The present review discusses about the significance of bioprinting technique and strategies employed for printability and to achieve porosity in the developed materials