Hemophagocytic Lymphohistiocytosis/Macrophage-Activation Syndrome
(HLH/MAS) Following Treatment with Tisagenlecleucel
CAR-T cell related HLH/MAS is an unusual manifestation of severe
cytokine release syndrome (CRS) with high mortality rates and a
challenging diagnosis. The establishment of specific diagnosis criteria
is essential, and the combination of several techniques for CAR-T cell
follow-up, allows a more precise management of this complication.