loading page

The genomic architecture of inversion clines in a grasshopper species group with a complex biogeographic history
  • +5
  • Noelia Guzman,
  • Petri Kemppainen,
  • Daniela Monti,
  • Elio Castillo,
  • Marcela Rodriguero,
  • Andres Sanchez-Restrepo,
  • Maria Cigliano,
  • Viviana Confalonieri
Noelia Guzman
UBA Faculty of Exact and Natural Sciences

Corresponding Author:[email protected]

Author Profile
Petri Kemppainen
Author Profile
Daniela Monti
UBA Faculty of Exact and Natural Sciences
Author Profile
Elio Castillo
Universidad Nacional de Misiones Facultad de Ciencias Exactas Quimicas y Naturales
Author Profile
Marcela Rodriguero
UBA Faculty of Exact and Natural Sciences
Author Profile
Andres Sanchez-Restrepo
UBA Faculty of Exact and Natural Sciences
Author Profile
Maria Cigliano
Universidad Nacional de la Plata
Author Profile
Viviana Confalonieri
UBA Faculty of Exact and Natural Sciences
Author Profile


Chromosomal inversions play a role in the adaptation and diversification of different systems, mainly due to supergenes resulting from recombination suppression. Supergenes are “clusters” of genes in linkage disequilibrium (LD) whose frequencies may be associated with environmental variables. The grasshopper “species complex” Trimerotropis pallidipennis is considered to have several genetic lineages distributed from North to South America in arid and semi-arid high-altitude environments. The southernmost lineage, Trimerotropis sp., bears 4 to 7 putative inversion polymorphisms with clinal variation, possibly allowing adaptation to temperate environments. We analyzed chromosomal, mitochondrial and genome-wide SNP markers in 19 Trimerotropis sp. populations mainly distributed along two altitudinal gradients (MS and Ju). We show that populations across Argentina are formed by two main chromosomally and genetically differentiated lineages: one distributed in the southernmost border of the “Andes Centrales”, adding evidence for a differentiation hotspot in this area; and the other widely distributed in Argentina. Within the latter, genomic architecture analysis revealed four clusters of loci in high LD that correspond to inversions, of which at least one is associated to a chromosomal rearrangement, confirming its status as “true inversion”. We demonstrated the stability of chromosome polymorphisms for more than 20 generations and the occurrence of non-neutral markers associated with inversions and environmental variables. Inversion clines could be the consequence of coupling between extrinsic postzygotic barriers, leading to a hybrid zone, and spatially varying selection along environmental gradients. These results provide a framework for future investigations about candidate genes implicated in the rapid adaptation to new environments.
18 Jul 2021Submitted to Molecular Ecology
04 Aug 2021Reviewer(s) Assigned
12 Oct 2021Review(s) Completed, Editorial Evaluation Pending
13 Oct 2021Editorial Decision: Revise Minor
25 Nov 2021Review(s) Completed, Editorial Evaluation Pending
25 Nov 20211st Revision Received
29 Nov 2021Editorial Decision: Accept