Detection and validation of six pathogenic variants in Chinese inherited
heart disease patients using clinical whole-exome sequencing
The targeted next-generation sequencing (NGS) was employed in detecting
the pathogenic mutations in inherited heart disease patients in the
present study. Two main methods, the NGS and the classic Sanger
sequencing, were used in this study. And, the whole-exome sequencing
(WES) was specifically used in this study.