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Reference values of impulse oscillometry (IOS) for healthy Chinese children aged 4-18 years
  • Jinhong Wu,
  • Hao Zhang
Jinhong Wu
Shanghai Children's Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine

Corresponding Author:[email protected]

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Hao Zhang
Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine
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Objective: To establish the predicted value of lung function determined by impulse oscillometry (IOS) in children (4~17 years old) in China. Methods: A total of 6270 healthy children aged 4 to 17 in Shanghai were included. The Master Screen IOS pulmonary function device (Jaeger Co, Germany) was used to detect the respiratory total impedance (Zrs), response frequency (Fres), viscosity resistance (Rrs) and elastic resistance (Xrs) at various oscillation frequencies, and the indexes above were analyzed. The stepwise multivariate regression was used to establish the regression equation of related parameters of IOS in different genders. Results The median age of 6270 children (3345 boys and 2925 girls) was 10 years, ranging from 4 to 17 years. The differences in the main IOS parameters between different age and height groups are statistically significant regardless of sex (P<0.05). The values of Z5, R5, R20, and Fres decreased with the increase of age and height, while X5 increased with the increase of age and height. The stepwise multivariate regression analysis showed that IOS parameters were related to height, age, and weight, and most IOS parameters were most closely related to height (the absolute value of regression coefficient was the largest). Conclusions: The study revealed the normal predicted value of pulmonary function by IOS in healthy children in China. In the evaluation of the results of the lung function measurements, the use of this predicted value equation is more in line with the characteristics of Chinese children than that of foreign countries. Key words: impulse oscillometry; respiratory function test; normal predicted value; child