Percutaneous mitral valve repair assisted by a catheter-based
circulatory support device in a heart transplant patient
Abstract Systemic infections and chronic graft rejection represent
common causes of mortality and morbidity in heart transplant patients.
In severe cases, cardiogenic shock (CS) may occur and require
hemodynamic stabilization with temporary mechanical circulatory support
(tempMCS).1 Under these devastating circumstances, treatment of sequelae
of left ventricular dysfunction, such as secondary mitral regurgitation
(MR) is challenging, especially when surgical repair is deemed futile.
In non-transplant patients, interventional mitral valve repair
strategies such as the MitraClip system (Abbott Cardiovascular,
Plymouth, MN, USA) have been used to successfully treat secondary MR and
allow for weaning from tempMCS.2 We report about the first patient in
whom profound cardiogenic shock after heart transplantation was
stabilized with tempMCS followed by interventional elimination of