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Impact of Nutritional Assessment on Long-Term Outcomes in Patients with Carotid Artery Stenting
  • Muhammed Demir,
  • Mehmet Ozbek
Muhammed Demir
Dicle University Medical Faculty
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Mehmet Ozbek
Dicle University Medical Faculty
Author Profile

Abstract

Objective: Malnutrition is associated with poor clinical outcomes in many diseases. The Controlling Nutritional Status (CONUT) is an objective index used for evaluating nutritional status of hospitalized patients. The aim of this study was to investigate the relationship between malnutrition assessed by CONUT score and the prognosis in patients undergoing carotid artery stenting (CAS). Methods: The study included 170 patients who underwent CAS due to symptomatic or asymptomatic severe carotid artery stenosis. Median follow-up period was 50 (interquartile range [IQR], 41-60) months. Patients were divided into two groups according to the CONUT score: (i) normal nutrition (<2) and (ii) malnutrition (≥2). Primary endpoint was accepted as MACE (major adverse cardiac events) including all-cause death and ischemic stroke. Results:The prevalence of MACE was significantly higher in the malnutrition group (p=0.001). Kaplan Meier analysis showed lower survival rates in the malnutrition group (log rank = 9.36, p=0.002; Figure 4). In multivariate logistic regression analysis, age and CONUT score were independent predictors of all-cause death and stroke after adjustment for confounding factors, respectively, (OR: 1.058, 95% CI: 1.013-1.105, p=0.011, OR: 1.318, 95% CI: 1.017-1.881, p=0.039). Conclusion: Higher CONUT scores were associated with adverse outcomes in patients with CAS. Malnutrition assessed by the CONUT score may provide valuable prognostic information in patients with CAS.

Peer review status:ACCEPTED

02 Jun 2021Submitted to International Journal of Clinical Practice
02 Jun 2021Submission Checks Completed
02 Jun 2021Assigned to Editor
20 Jun 2021Reviewer(s) Assigned
06 Jul 2021Review(s) Completed, Editorial Evaluation Pending
16 Jul 2021Editorial Decision: Revise Major
18 Jul 20211st Revision Received
21 Jul 2021Submission Checks Completed
21 Jul 2021Assigned to Editor
21 Jul 2021Review(s) Completed, Editorial Evaluation Pending
21 Jul 2021Editorial Decision: Accept