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Clinical Pharmacist’s Contribution on Treatment Adherence and Quality of Life in Patients with Stroke: A prospective, controlled, clinical pharmacist led-educational study
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  • Oğuzhan Fırat,
  • Ethem Murat Arsava,
  • Canan Togay-Isıkay,
  • Merve Basol,
  • Mehmet A. Topcuoglu,
  • Kutay Demirkan
Oğuzhan Fırat
Hacettepe University Faculty of Pharmacy
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Ethem Murat Arsava
Hacettepe University Faculty of Medicine
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Canan Togay-Isıkay
Ankara University Faculty of Medicine
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Merve Basol
Hacettepe University Faculty of Medicine
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Mehmet A. Topcuoglu
Hacettepe University Faculty of Medicine
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Kutay Demirkan
Hacettepe University Faculty of Pharmacy
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Abstract

Background: Stroke is one of the leading causes of repetitive and disability, affecting the quality of life of the patients negatively, causing depressive symptoms. Aim: The aim of this study was to determine the clinical pharmacist’s contribution on treatment adherence and quality of life (QOL) in patients with stroke, and assessing patient’s satisfaction. Methods: A total of 98 patients with first-ever stroke were included in the study and followed up by for 3 months. This interventional 2-phase study was conducted sequentially at two different university hospitals. Patients in intervention group (IG) was given education by clinical pharmacist and patient in control group (CG) was only given routine care. Medication adherence and QOL was assessed at discharge day, 1st and 3rd month after discharge. Results: The increase in treatment adherence of the patients in IG was significant over time (p<0.001). The scores of the patients in IG from the ‘energy’ and ‘work/productivity’ subscales at 1st and 3rd months after discharge were higher than the patients in CG (p<0.05). The patient’s satisfaction in IG was also higher than the patients in CG (p<0.001). Conclusion: Clinical pharmacist-led education is beneficial to improve treatment adherence and patient’s satisfaction in patients with first ever stroke. Clinical pharmacist should be integrated to improve QOL and treatment adherence multidisciplinary team consisting physician, nurse and physiotherapist. Further studies are needed to assess the impact of clinical pharmacists’ interventions on protection from the second stroke of these patients.